Across TCGA patient cohorts, FAM180B mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM180B-associated genes across cancer lineages are Stathmin, TIGAR, and c-Jun_pS73. Each is linked with FAM180B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM180B-to-partner and partner-to-FAM180B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM180B→partner) and Y-score (partner→FAM180B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Stathmin →	+0.162	+3.000	.041	.037	3	1
UCEC	TIGAR →	+0.214	+3.026	.015	.019	3	1
UCEC	c-Jun_pS73 →	-0.193	-3.000	.035	.037	3	1
UCEC	4E-BP1 →	+0.328	+2.837	.036	.035	3	1
UCEC	ATM →	-0.730	-3.000	.005	.037	2	1
UCEC	JNK2 →	+0.305	+3.000	.007	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

FAM180B survival (RNA) · tumor vs normal (RNA) · all FAM180B data types