Across TCGA cell cohorts, FAM180B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,683 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FAM180B-associated GO terms across cancer lineages are Positive regulation of intracellular estrogen receptor signaling pathway, mRNA alternative polyadenylation, and mRNA export from nucleus. Each is linked with FAM180B in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM180B-to-partner and partner-to-FAM180B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM180B→partner) and Y-score (partner→FAM180B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.115	+0.088	<.001	.008	3	8
BREAST	mRNA alternative polyadenylation →	+0.076	+0.076	<.001	<.001	3	8
BREAST	mRNA export from nucleus →	+0.059	+0.054	.009	.004	3	8
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.152	+0.096	<.001	<.001	3	7
BLOOD_Myeloma	Negative regulation of cell cycle phase transition →	+0.041	+0.082	.001	.001	3	7
SKIN	Negative regulation of ribosome biogenesis →	+0.115	+0.858	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,683 associations by consensus.

Exploration

FAM180B survival (RNA) · tumor vs normal (RNA) · all FAM180B data types