FAM177A1

Across TCGA pan-cancer cohorts, FAM177A1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM177A1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM177A1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM177A1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where FAM177A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.402	0.796	<.001	43	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LSCC	DFS	Tertile	III,IV	0.417	0.874	.033	4	view →
CCRCC	DFS	Median	III,IV	1.000	0.451	.032	2	view →
HNSC	OS	Quartile	All	0.590	0.819	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAM177A1–LUAD (DFS)

Open the LUAD breakdown →