FAM177A1

Across TCGA patient cohorts, FAM177A1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,331 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM177A1-associated genes across cancer lineages are NALCN, SRP54, and DAD1. Each is linked with FAM177A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM177A1-to-partner and partner-to-FAM177A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM177A1 versus NALCN in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM177A1→partner) and Y-score (partner→FAM177A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NALCN →	+1.037	+0.418	<.001	.001	3	4
HNSC	SRP54 →	+0.556	+0.355	<.001	.004	3	4
OV	DAD1 →	+0.584	+0.275	<.001	<.001	3	4
OV	RTRAF →	+0.463	+0.282	.003	<.001	3	4
LUAD	SCFD1 →	+0.312	+0.270	<.001	<.001	3	4
CCRCC	BCL2L2 →	+0.363	+0.261	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,331 associations by consensus.

FAM177A1 vs NALCN — GBM

Explore this scatter interactively →