FAM177A1

Across TCGA patient cohorts, FAM177A1 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM177A1-associated genes across cancer lineages are HMGA1P7, LINC01707, and DPPA2P2. Each is linked with FAM177A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM177A1-to-partner and partner-to-FAM177A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGA1P7 grouped by FAM177A1-low versus FAM177A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM177A1→partner) and Y-score (partner→FAM177A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HMGA1P7 →	+0.126	+5.003	<.001	.004	3	1
COAD	LINC01707 →	+0.142	+4.693	.003	.007	3	1
COAD	DPPA2P2 →	+0.098	+5.122	.004	.004	3	1
COAD	LINC01812 →	+0.183	+4.237	.001	.008	3	1
COAD	HSPE1P20 →	+0.206	+4.602	<.001	.008	3	1
COAD	MIR4314 →	+0.446	+5.917	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

HMGA1P7 by FAM177A1 expression — COAD

Explore this box plot interactively →