FAM177A1

Across TCGA cell cohorts, FAM177A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,549 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM177A1-associated GO terms across cancer lineages are SRP-dependent cotranslational protein targeting to membrane, translocation, Vacuolar transport, and Retrograde transport, endosome to Golgi. Each is linked with FAM177A1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FAM177A1-to-partner and partner-to-FAM177A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRP-dependent cotranslational protein targeting to membrane, translocation grouped by FAM177A1-low versus FAM177A1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM177A1→partner) and Y-score (partner→FAM177A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SRP-dependent cotranslational protein targeting to membrane, translocation →	+0.169	+1.223	<.001	<.001	3	12
BREAST	Vacuolar transport →	+0.058	+0.865	.001	.003	3	11
SOFT_TISSUE	Retrograde transport, endosome to Golgi →	+0.071	+0.881	<.001	<.001	3	11
KIDNEY	Regulation of ubiquitin-dependent protein catabolic process →	+0.061	+0.962	<.001	<.001	3	10
KIDNEY	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.063	+0.832	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.056	+0.626	.004	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,549 associations by consensus.

SRP-dependent cotranslational protein targeting to membrane, translocation by FAM177A1 expression — OESOPHAGUS

Explore this box plot interactively →