Across TCGA patient cohorts, FAM174C RNA expression is significantly associated with the protein abundance of many other proteins, with 12,395 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM174C-associated proteins across cancer lineages are IQSEC1, P2RY8_S324, and CLPP. Each is linked with FAM174C in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM174C-to-partner and partner-to-FAM174C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174C→partner) and Y-score (partner→FAM174C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IQSEC1 →	-0.320	-0.269	.003	.007	3	4
LSCC	P2RY8_S324 →	-0.913	-0.549	<.001	<.001	3	4
PDAC	CLPP →	+0.261	+0.313	<.001	<.001	3	4
COAD	YJU2 →	+0.250	+0.346	.008	.007	3	3
GBM	RABEP2 →	+0.176	+0.405	.002	.001	3	3
GBM	RALGAPA1 →	-0.234	-0.373	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,395 associations by consensus.

Exploration

FAM174C survival (RNA) · tumor vs normal (RNA) · all FAM174C data types