Across TCGA patient cohorts, FAM174C mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM174C-associated genes across cancer lineages are RN7SL392P, UCHL1-AS1, and RNU7-81P. Each is linked with FAM174C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM174C-to-partner and partner-to-FAM174C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174C→partner) and Y-score (partner→FAM174C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL392P →	+0.082	+4.884	<.001	.004	3	2
SKCM	UCHL1-AS1 →	+0.100	+3.838	<.001	.006	3	1
SKCM	RNU7-81P →	+0.310	+4.743	<.001	.005	3	1
SKCM	RNU6-494P →	+0.494	+4.884	<.001	.004	3	1
SKCM	OR5BT1P →	+0.104	+4.135	.001	.004	3	1
SKCM	LINC02307 →	+0.372	+4.855	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

Exploration

FAM174C survival (RNA) · tumor vs normal (RNA) · all FAM174C data types