Across TCGA cell cohorts, FAM174C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,423 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FAM174C-associated GO terms across cancer lineages are Cytoplasm protein quality control by the ubiquitin-proteasome system, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with FAM174C in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM174C-to-partner and partner-to-FAM174C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174C→partner) and Y-score (partner→FAM174C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.192	+0.773	<.001	.003	3	14
PANCREAS	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.091	+0.812	<.001	<.001	3	14
PANCREAS	Electron transport coupled proton transport →	+0.091	+0.812	<.001	<.001	3	14
PANCREAS	Pigment metabolic process involved in pigmentation →	+0.233	+0.703	<.001	<.001	3	10
LUNG_SCLC	Regulation of cellular hyperosmotic salinity response →	+0.165	+0.594	.008	.006	3	10
LUNG_SCLC	Regulation of response to salt stress →	+0.165	+0.594	.008	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,423 associations by consensus.

Exploration

FAM174C survival (RNA) · tumor vs normal (RNA) · all FAM174C data types