Across TCGA patient cohorts, FAM174B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,443 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM174B-associated proteins across cancer lineages are MYO5C, ARFGEF3, and RAP1GAP. Each is linked with FAM174B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM174B-to-partner and partner-to-FAM174B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174B→partner) and Y-score (partner→FAM174B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYO5C →	+0.670	+1.301	<.001	<.001	3	7
GBM	ARFGEF3 →	+0.484	+0.318	<.001	.006	3	7
COAD	RAP1GAP →	+0.911	+1.336	<.001	<.001	3	6
CCRCC	STAT1 →	-0.524	-0.524	.001	<.001	3	6
BRCA	AGR2 →	+1.526	+1.702	<.001	<.001	3	6
UCEC	ELAPOR1 →	+1.019	+0.809	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,443 associations by consensus.

Exploration

FAM174B survival (RNA) · tumor vs normal (RNA) · all FAM174B data types