Across TCGA patient cohorts, FAM174B protein abundance is significantly associated with the RNA expression of many other genes, with 5,141 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM174B-associated genes across cancer lineages are C9orf152, SPDEF, and SCRN3. Each is linked with FAM174B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM174B-to-partner and partner-to-FAM174B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174B→partner) and Y-score (partner→FAM174B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C9orf152 →	+1.754	+0.737	.004	<.001	3	4
BRCA	SPDEF →	+2.448	+0.685	.001	<.001	3	4
COAD	SCRN3 →	+0.652	+0.840	.001	.002	3	3
LUAD	PEX11A →	+0.549	+0.430	<.001	.001	3	3
OV	LINC00494 →	-1.125	-0.715	.007	.003	3	3
LUAD	TFF3 →	+3.294	+0.833	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,141 associations by consensus.

Exploration

FAM174B survival (RNA) · tumor vs normal (RNA) · all FAM174B data types