Across TCGA patient cohorts, FAM174B mutation is significantly associated with the RNA expression of many other genes, with 1,654 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM174B-associated genes across cancer lineages are RN7SL369P, RPL12P24, and RNU105B. Each is linked with FAM174B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM174B-to-partner and partner-to-FAM174B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174B→partner) and Y-score (partner→FAM174B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL369P →	+0.110	+3.411	<.001	.009	3	2
CESC	RPL12P24 →	+0.122	+4.231	<.001	<.001	3	2
HNSC	RNU105B →	+0.205	+5.069	<.001	.008	3	2
BRCA	AQP7P4 →	+0.067	+4.995	<.001	.009	3	2
CESC	PATE3 →	+0.035	+3.542	.007	.007	3	1
CESC	ATP5PFP1 →	+0.188	+3.575	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,654 associations by consensus.

Exploration

FAM174B survival (RNA) · tumor vs normal (RNA) · all FAM174B data types