FAM174A

Across TCGA patient cohorts, FAM174A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,849 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM174A-associated proteins across cancer lineages are CAST, XPO5, and NUP50. Each is linked with FAM174A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM174A-to-partner and partner-to-FAM174A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM174A versus CAST in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174A→partner) and Y-score (partner→FAM174A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CAST →	+0.430	+0.482	<.001	.002	3	6
LSCC	XPO5 →	-0.539	-0.438	.002	.008	3	5
BRCA	NUP50 →	-0.318	-0.948	<.001	<.001	3	5
BRCA	SCAMP1 →	+0.596	+0.951	<.001	<.001	3	5
GBM	MAPRE1 →	-0.221	-0.320	.001	<.001	3	5
GBM	SMCHD1 →	-0.325	-0.342	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,849 associations by consensus.

FAM174A vs CAST — LSCC

Explore this scatter interactively →