FAM174A

Across TCGA patient cohorts, FAM174A protein abundance is significantly associated with the RNA expression of many other genes, with 5,228 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM174A-associated genes across cancer lineages are ELL2, RPIA, and PCSK6. Each is linked with FAM174A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM174A-to-partner and partner-to-FAM174A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM174A versus ELL2 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174A→partner) and Y-score (partner→FAM174A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ELL2 →	+0.616	+0.499	.003	.003	3	4
COAD	RPIA →	-0.546	-0.373	.005	.004	3	3
BRCA	PCSK6 →	+1.078	+0.650	<.001	<.001	3	3
BRCA	TEX30 →	-0.650	-0.492	.001	.002	3	3
OV	MPP2 →	-0.715	-0.529	.004	.002	3	2
BRCA	SCGB2A2 →	+2.952	+0.450	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,228 associations by consensus.

FAM174A vs ELL2 — BRCA

Explore this scatter interactively →