FAM174A

Across TCGA patient cohorts, FAM174A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM174A-associated genes across cancer lineages are Astrocytes, Adipocytes, and MPP. Each is linked with FAM174A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM174A-to-partner and partner-to-FAM174A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by FAM174A-low versus FAM174A-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174A→partner) and Y-score (partner→FAM174A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Astrocytes →	+0.067	+3.500	.016	.017	3	2
COAD	Adipocytes →	+0.036	+2.753	.011	.017	3	1
STAD	MPP →	+0.020	+2.809	.004	.040	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Astrocytes by FAM174A expression — LUAD

Explore this box plot interactively →