FAM174A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM174A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM174A-associated genes across cancer lineages are OR4F15. Each is linked with FAM174A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM174A-to-partner and partner-to-FAM174A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F15 grouped by FAM174A-low versus FAM174A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM174A→partner) and Y-score (partner→FAM174A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR4F15 →+0.015+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR4F15 by FAM174A expression — LARGE_INTESTINE

Box plot of OR4F15 in FAM174A-low vs FAM174A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration