FAM172BP

Across TCGA patient cohorts, FAM172BP mutation is significantly associated with the RNA expression of many other genes, with 423 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM172BP-associated genes across cancer lineages are HMGB1P24, NGRN, and KMT5A. Each is linked with FAM172BP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM172BP-to-partner and partner-to-FAM172BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGB1P24 grouped by FAM172BP-low versus FAM172BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM172BP→partner) and Y-score (partner→FAM172BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMGB1P24 →	+0.378	+3.523	<.001	.002	3	1
UCEC	NGRN →	+0.654	+3.470	.003	.003	3	1
UCEC	KMT5A →	+0.583	+3.370	<.001	.004	3	1
UCEC	SREBF2-AS1 →	+0.616	+3.513	<.001	.002	3	1
UCEC	PGP →	+0.586	+3.459	.004	.005	3	1
UCEC	CMC1 →	+0.436	+3.502	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 423 associations by consensus.

HMGB1P24 by FAM172BP expression — UCEC

Explore this box plot interactively →