FAM172BP

Across TCGA patient cohorts, FAM172BP mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM172BP-associated genes across cancer lineages are Ku80, C-Raf, and p70-S6K_pT389. Each is linked with FAM172BP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM172BP-to-partner and partner-to-FAM172BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by FAM172BP-low versus FAM172BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM172BP→partner) and Y-score (partner→FAM172BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.315	+3.183	.015	.010	3	1
UCEC	C-Raf →	+0.261	+3.169	<.001	.020	3	1
UCEC	p70-S6K_pT389 →	-0.266	-3.160	.010	.019	2	1
UCEC	EGFR_pY1068 →	-0.390	-3.169	.004	.020	1	1
UCEC	A-Raf_pS299 →	-0.179	-3.169	.006	.020	1	1
UCEC	JNK2 →	+0.438	+3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Ku80 by FAM172BP expression — UCEC

Explore this box plot interactively →