FAM171A2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM171A2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,582 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM171A2-associated genes across cancer lineages are S1PR5, RASAL3, and SLC12A7. Each is linked with FAM171A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM171A2-to-partner and partner-to-FAM171A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM171A2 versus S1PR5 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171A2→partner) and Y-score (partner→FAM171A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMS1PR5 →+0.650+0.239.002.00132
LSCCRASAL3 →-0.770-0.723.003.00232
OVSLC12A7 →-0.747-0.476.001.00832
OVBICC1 →-1.081-0.435.001.00132
OVAPOL2 →-1.054-0.526.006.00532
LSCCSAA2 →-1.217-0.527.004.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,582 associations by consensus.

FAM171A2 vs S1PR5 — GBM

Per-sample scatter of FAM171A2 vs S1PR5 in GBM (Pearson r = 0.33).

Explore this scatter interactively →

Exploration