FAM171A2

Across TCGA patient cohorts, FAM171A2 mutation is significantly associated with the RNA expression of many other genes, with 131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM171A2-associated genes across cancer lineages are RN7SL470P, PPP1R9A-AS1, and ATXN3L. Each is linked with FAM171A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM171A2-to-partner and partner-to-FAM171A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL470P grouped by FAM171A2-low versus FAM171A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171A2→partner) and Y-score (partner→FAM171A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL470P →	+0.288	+2.694	<.001	.005	3	2
UCEC	PPP1R9A-AS1 →	+0.272	+3.539	<.001	.005	3	2
CESC	ATXN3L →	+0.031	+5.837	<.001	.001	3	1
CESC	DAOA →	+0.036	+4.760	<.001	.003	3	1
CESC	RNA5SP432 →	+0.255	+4.539	.001	.008	3	1
CESC	SUMO2P13 →	+0.169	+4.193	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 131 associations by consensus.

RN7SL470P by FAM171A2 expression — UCEC

Explore this box plot interactively →