FAM171A2

Across TCGA cell cohorts, FAM171A2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible FAM171A2-associated genes across cancer lineages are OR2B3, POTEB2, and CLDN17. Each is linked with FAM171A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM171A2-to-partner and partner-to-FAM171A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2B3 grouped by FAM171A2-low versus FAM171A2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171A2→partner) and Y-score (partner→FAM171A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR2B3 →	+0.015	+4.285	<.001	.007	3	2
STOMACH	POTEB2 →	+0.005	+4.285	<.001	.007	3	2
LARGE_INTESTINE	CLDN17 →	+0.042	+3.345	.005	.007	3	1
LARGE_INTESTINE	BPIFB6 →	+0.016	+4.022	<.001	.006	3	1
LARGE_INTESTINE	RIPPLY2 →	+0.492	+3.196	<.001	.007	3	1
LARGE_INTESTINE	TBC1D3K →	+0.314	+3.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR2B3 by FAM171A2 expression — STOMACH

Explore this box plot interactively →