FAM171A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM171A1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,498 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM171A1-associated genes across cancer lineages are SEMA3G, OCA2, and PTGDS. Each is linked with FAM171A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM171A1-to-partner and partner-to-FAM171A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM171A1 versus SEMA3G in CCRCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171A1→partner) and Y-score (partner→FAM171A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCSEMA3G →+0.990+0.385<.001<.00133
BRCAOCA2 →+1.360+0.776<.001<.00133
GBMPTGDS →+1.069+0.541<.001<.00133
BRCADUSP22 →+0.584+0.623.002.00233
CCRCCPTPRB →+0.899+0.381<.001<.00133
GBMDUSP26 →+1.678+0.554<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,498 associations by consensus.

FAM171A1 vs SEMA3G — CCRCC

Per-sample scatter of FAM171A1 vs SEMA3G in CCRCC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration