FAM171A1

Across TCGA patient cohorts, FAM171A1 mutation is significantly associated with the RNA expression of many other genes, with 3,752 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM171A1-associated genes across cancer lineages are BUB3, EME1, and CIP2A. Each is linked with FAM171A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM171A1-to-partner and partner-to-FAM171A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BUB3 grouped by FAM171A1-low versus FAM171A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171A1→partner) and Y-score (partner→FAM171A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BUB3 →	+0.422	+2.212	<.001	<.001	3	3
UCEC	EME1 →	+0.428	+2.457	.002	.001	3	3
UCEC	CIP2A →	+0.521	+1.784	.002	<.001	3	3
UCEC	NOLC1 →	+0.371	+1.430	.007	.002	3	3
UCEC	CENPN →	+0.806	+2.828	<.001	<.001	3	3
UCEC	LONRF3 →	+0.346	+1.805	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,752 associations by consensus.

BUB3 by FAM171A1 expression — UCEC

Explore this box plot interactively →