FAM171A1

Across TCGA cell cohorts, FAM171A1 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM171A1-associated genes across cancer lineages are LRIT1, NKX2-6, and TEX46. Each is linked with FAM171A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM171A1-to-partner and partner-to-FAM171A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRIT1 grouped by FAM171A1-low versus FAM171A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171A1→partner) and Y-score (partner→FAM171A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LRIT1 →	+0.027	+4.099	<.001	<.001	3	2
BLOOD_Leukemia	NKX2-6 →	+0.278	+3.786	<.001	.002	3	2
LARGE_INTESTINE	TEX46 →	+0.202	+3.719	<.001	.001	3	2
UPPER_AERODIGESTIVE_TRACT	FAM236A →	+0.120	+5.357	<.001	.003	3	1
LUNG_NSCLC_LUAD	SLC18B1 →	+0.801	+3.206	.009	.006	3	1
LUNG_NSCLC_LUAD	PARS2 →	+0.400	+3.279	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

LRIT1 by FAM171A1 expression — BLOOD_Leukemia

Explore this box plot interactively →