FAM170A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM170A protein abundance is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM170A-associated genes across cancer lineages are ARFRP1, VWA5A, and GPRC5D. Each is linked with FAM170A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM170A-to-partner and partner-to-FAM170A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM170A versus ARFRP1 in COAD, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM170A→partner) and Y-score (partner→FAM170A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADARFRP1 →-0.876-1.137.008<.00131
COADVWA5A →+1.088+0.957.003.00931
COADGPRC5D →+0.297+1.027.003.00431
COADAPOBEC1 →+1.750+1.468.004.00131
COADARRDC3 →+0.828+1.271.004<.00131
COADKAT2B →+0.721+1.104.008.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

FAM170A vs ARFRP1 — COAD

Per-sample scatter of FAM170A vs ARFRP1 in COAD (Pearson r = -0.53).

Explore this scatter interactively →

Exploration