Across TCGA patient cohorts, FAM169A mutation is significantly associated with the RNA expression of many other genes, with 1,497 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM169A-associated genes across cancer lineages are RPS6P8, OSBPL9P5, and USP9YP15. Each is linked with FAM169A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM169A-to-partner and partner-to-FAM169A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM169A→partner) and Y-score (partner→FAM169A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPS6P8 →	+0.254	+3.107	<.001	.003	3	3
COAD	OSBPL9P5 →	+0.198	+4.927	<.001	.002	3	3
BRCA	USP9YP15 →	+0.084	+8.471	<.001	.005	3	2
UCEC	CCDC3 →	-0.992	-4.087	<.001	<.001	3	2
UCEC	HAUS1 →	+0.543	+2.592	.006	.006	3	2
UCEC	VPS26C →	+0.422	+3.337	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,497 associations by consensus.

Exploration

FAM169A survival (RNA) · tumor vs normal (RNA) · all FAM169A data types