Across TCGA patient cohorts, FAM169A mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM169A-associated genes across cancer lineages are EGFR_pY1068, ASNS, and ATM. Each is linked with FAM169A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM169A-to-partner and partner-to-FAM169A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM169A→partner) and Y-score (partner→FAM169A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.240	-2.000	.034	.032	3	2
UCEC	ASNS →	+0.349	+3.169	.032	.019	3	2
COAD	ATM →	-0.635	-3.000	.001	.035	3	2
COAD	RAD51 →	+0.181	+3.008	.026	.019	3	2
UCEC	EGFR →	-0.243	-2.973	<.001	.035	3	1
UCEC	FoxM1 →	+0.259	+2.700	.026	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

FAM169A survival (RNA) · tumor vs normal (RNA) · all FAM169A data types