FAM168A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM168A protein abundance is significantly associated with the RNA expression of many other genes, with 12,997 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FAM168A-associated genes across cancer lineages are RNF121, EDNRA, and RAB6A. Each is linked with FAM168A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM168A-to-partner and partner-to-FAM168A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM168A versus RNF121 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM168A→partner) and Y-score (partner→FAM168A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNF121 →+0.594+0.348.009.00126
COADEDNRA →+0.877+0.336.003.00135
HNSCRAB6A →+0.777+0.355<.001<.00135
COADTCF4 →+0.749+0.374<.001<.00135
BRCAFERMT2 →+0.731+0.301.001.00235
HNSCEMSY →+0.780+0.458<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,997 associations by consensus.

FAM168A vs RNF121 — HNSC

Per-sample scatter of FAM168A vs RNF121 in HNSC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration