FAM168A

Across TCGA patient cohorts, FAM168A mutation is significantly associated with the RNA expression of many other genes, with 246 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM168A-associated genes across cancer lineages are CINP, SGTA, and TIMM44. Each is linked with FAM168A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM168A-to-partner and partner-to-FAM168A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CINP grouped by FAM168A-low versus FAM168A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM168A→partner) and Y-score (partner→FAM168A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CINP →	+0.345	+3.201	.006	.009	3	1
UCEC	SGTA →	+0.612	+3.480	<.001	.002	3	1
UCEC	TIMM44 →	+0.444	+3.369	.006	.005	3	1
UCEC	PIGL →	+0.486	+3.513	.001	.002	3	1
UCEC	DPH1 →	+0.651	+3.459	.001	.005	3	1
UCEC	CEP104 →	+0.539	+3.202	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 246 associations by consensus.

CINP by FAM168A expression — UCEC

Explore this box plot interactively →