FAM168A

Across TCGA cell cohorts, FAM168A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,237 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM168A-associated GO terms across cancer lineages are Regulation of intracellular steroid hormone receptor signaling pathway, Positive regulation of organelle assembly, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with FAM168A in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM168A-to-partner and partner-to-FAM168A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular steroid hormone receptor signaling pathway grouped by FAM168A-low versus FAM168A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM168A→partner) and Y-score (partner→FAM168A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.078	+0.807	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.073	+1.524	<.001	<.001	3	16
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.084	+0.672	.003	.001	3	15
LUNG_SCLC	Regulation of base-excision repair →	+0.134	+0.758	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of smoothened signaling pathway →	+0.079	+1.259	.002	.004	3	15
STOMACH	Regulation of G1/S transition of mitotic cell cycle →	+0.075	+1.063	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,237 associations by consensus.

Regulation of intracellular steroid hormone receptor signaling pathway by FAM168A expression — LUNG_SCLC

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