FAM168A

Across TCGA cell cohorts, FAM168A mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM168A-associated genes across cancer lineages are CCDC172, OR12D3, and GPR42. Each is linked with FAM168A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM168A-to-partner and partner-to-FAM168A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by FAM168A-low versus FAM168A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM168A→partner) and Y-score (partner→FAM168A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCDC172 →	+0.079	+4.544	<.001	.003	3	1
LARGE_INTESTINE	OR12D3 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GPR42 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	SBK2 →	+0.479	+4.000	<.001	.004	3	1
LARGE_INTESTINE	GK2 →	+0.008	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CCDC172 by FAM168A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →