Across TCGA patient cohorts, FAM166B mutation is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM166B-associated genes across cancer lineages are MIR1251, URGCP-MRPS24, and MIR7702. Each is linked with FAM166B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM166B-to-partner and partner-to-FAM166B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM166B→partner) and Y-score (partner→FAM166B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MIR1251 →	+0.600	+5.267	<.001	.001	3	2
UCEC	URGCP-MRPS24 →	+0.313	+3.836	<.001	.001	3	1
UCEC	MIR7702 →	+0.373	+5.060	<.001	.001	3	1
UCEC	IGHV4-4 →	+1.270	+3.175	<.001	.002	3	1
UCEC	MIR8071-2 →	+1.532	+2.935	<.001	.005	3	1
UCEC	IGHV1OR21-1 →	+0.896	+3.970	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

Exploration

FAM166B survival (RNA) · tumor vs normal (RNA) · all FAM166B data types