Across TCGA cell cohorts, FAM166B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,565 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FAM166B-associated GO terms across cancer lineages are Negative regulation of actin filament depolymerization, Endoplasmic reticulum localization, and Heme B biosynthetic process. Each is linked with FAM166B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM166B-to-partner and partner-to-FAM166B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM166B→partner) and Y-score (partner→FAM166B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of actin filament depolymerization →	-0.134	-0.330	<.001	<.001	3	6
PANCREAS	Endoplasmic reticulum localization →	-0.158	-0.188	.001	.005	2	7
UPPER_AERODIGESTIVE_TRACT	Heme B biosynthetic process →	+0.080	+0.334	.006	.008	3	5
LUNG_SCLC	Mitochondrial DNA metabolic process →	+0.093	+0.348	<.001	.001	3	5
LARGE_INTESTINE	tRNA transcription by RNA polymerase III →	+0.062	+0.304	.002	.009	3	5
UPPER_AERODIGESTIVE_TRACT	Protoporphyrinogen IX metabolic process →	+0.080	+0.334	.006	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,565 associations by consensus.

Exploration

FAM166B survival (RNA) · tumor vs normal (RNA) · all FAM166B data types