Across TCGA patient cohorts, FAM166A mutation is significantly associated with the RNA expression of many other genes, with 785 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM166A-associated genes across cancer lineages are TBC1D3P4, MTND6P9, and NIPA2P5. Each is linked with FAM166A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM166A-to-partner and partner-to-FAM166A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM166A→partner) and Y-score (partner→FAM166A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBC1D3P4 →	+0.039	+5.721	.002	.003	3	2
BRCA	MTND6P9 →	+0.158	+5.540	<.001	.004	3	2
SKCM	NIPA2P5 →	+0.064	+4.199	<.001	.009	3	2
COAD	MIR551A →	+0.323	+5.557	.002	.001	3	2
LUSC	PDE4DIPP3 →	+0.073	+3.974	<.001	.006	3	2
SKCM	TRAJ37 →	+0.605	+3.356	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 785 associations by consensus.

Exploration

FAM166A survival (RNA) · tumor vs normal (RNA) · all FAM166A data types