Across TCGA cell cohorts, FAM166A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,529 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible FAM166A-associated GO terms across cancer lineages are Response to methylglyoxal, Methylglyoxal catabolic process, and Methylglyoxal metabolic process. Each is linked with FAM166A in more than 11 cancer types. Because this analysis shows association rather than direction, both FAM166A-to-partner and partner-to-FAM166A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM166A→partner) and Y-score (partner→FAM166A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to methylglyoxal →	+0.125	+0.471	<.001	<.001	2	12
STOMACH	Methylglyoxal catabolic process →	+0.184	+0.238	<.001	.001	3	11
URINARY_TRACT	Methylglyoxal metabolic process →	+0.123	+0.248	.007	.005	2	12
BREAST	Cellular response to methylglyoxal →	+0.125	+0.471	<.001	<.001	2	12
BREAST	Cellular detoxification of methylglyoxal →	+0.125	+0.471	<.001	<.001	2	12
LARGE_INTESTINE	Transcription pausing by RNA polymerase II →	+0.110	+0.213	.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,529 associations by consensus.

Exploration

FAM166A survival (RNA) · tumor vs normal (RNA) · all FAM166A data types