Across TCGA cell cohorts, FAM162B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM162B-associated genes across cancer lineages are BPIFA1, ZNF541, and LINGO4. Each is linked with FAM162B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM162B-to-partner and partner-to-FAM162B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM162B→partner) and Y-score (partner→FAM162B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFA1 →	+0.156	+3.425	<.001	<.001	3	1
LARGE_INTESTINE	ZNF541 →	+0.199	+2.836	<.001	.009	2	1
LARGE_INTESTINE	LINGO4 →	+0.150	+2.869	<.001	.008	2	1
LARGE_INTESTINE	REELD1 →	+0.104	+3.555	<.001	.003	2	1
LARGE_INTESTINE	MSH4 →	+0.283	+3.464	.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

FAM162B survival (RNA) · tumor vs normal (RNA) · all FAM162B data types