Across TCGA cell cohorts, FAM162B mutation is significantly associated with the mutation status of many other genes, with 1,523 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM162B-associated genes across cancer lineages are ORC1, POMGNT1, and HSD17B2. Each is linked with FAM162B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM162B-to-partner and partner-to-FAM162B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM162B→partner) and Y-score (partner→FAM162B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ORC1 →	+2.222	+2.925	.001	.001	1	1
LARGE_INTESTINE	POMGNT1 →	+2.321	+2.643	.004	.004	1	1
LARGE_INTESTINE	HSD17B2 →	+4.392	+4.000	<.001	<.001	1	1
LARGE_INTESTINE	HUWE1 →	+1.444	+2.718	.006	.006	1	1
LARGE_INTESTINE	ADAMTS2 →	+2.222	+2.925	.001	.001	1	1
LARGE_INTESTINE	SF3B2 →	+2.392	+3.050	.001	.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,523 associations by consensus.

Exploration

FAM162B survival (RNA) · tumor vs normal (RNA) · all FAM162B data types