Across TCGA pan-cancer cohorts, FAM162A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM162A data layer compared with 24 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher FAM162A mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM162A expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.
COAD, CCRCC, and LSCC are the cancer types where FAM162A mass-spec protein most reproducibly stratifies survival.