FAM162A

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FAM162A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM162A data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FAM162A mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM162A expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, CCRCC, and LSCC are the cancer types where FAM162A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll1.0000.918.01236view →
CCRCCDFSMedianIII,IV0.4260.718.01420view →
LSCCDFSMedianAll0.9790.897.0177view →
HNSCDFSQuartileII,III,IV0.9560.713.0175view →
PDACDFSQuartileAll0.3510.588.0422view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAM162A–COAD (DFS)

Kaplan–Meier survival curve for FAM162A mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration