FAM162A

Across TCGA patient cohorts, FAM162A mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM162A-associated genes across cancer lineages are RNU6-995P, RN7SKP221, and TRDD1. Each is linked with FAM162A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM162A-to-partner and partner-to-FAM162A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-995P grouped by FAM162A-low versus FAM162A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM162A→partner) and Y-score (partner→FAM162A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-995P →	+0.271	+7.471	<.001	.008	3	1
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	1
BRCA	TRDD1 →	+0.910	+8.057	<.001	.005	3	1
UCEC	RNA5SP414 →	+0.731	+2.933	<.001	.006	3	1
UCEC	HNRNPCL3 →	+0.059	+2.871	<.001	.007	3	1
UCEC	MIR8078 →	+0.555	+2.785	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

RNU6-995P by FAM162A expression — BRCA

Explore this box plot interactively →