FAM162A

Across TCGA patient cohorts, FAM162A mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM162A-associated genes across cancer lineages are Annexin_VII, Caspase-8, and TFRC. Each is linked with FAM162A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM162A-to-partner and partner-to-FAM162A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin_VII grouped by FAM162A-low versus FAM162A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM162A→partner) and Y-score (partner→FAM162A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin_VII →	-0.216	-3.000	.007	.037	3	1
UCEC	Caspase-8 →	-0.294	-3.000	.043	.036	3	1
UCEC	TFRC →	+0.801	+3.000	.008	.036	2	1
UCEC	C-Raf →	+0.266	+3.000	.001	.036	2	1
UCEC	JNK2 →	+0.291	+3.000	.011	.037	1	1
UCEC	p62 Lck ligand →	+0.496	+3.000	.008	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Annexin_VII by FAM162A expression — UCEC

Explore this box plot interactively →