FAM161A

Across TCGA patient cohorts, FAM161A protein abundance is significantly associated with the RNA expression of many other genes, with 2,106 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM161A-associated genes across cancer lineages are TRAF3, RNASEH1-AS1, and TGFBR3L. Each is linked with FAM161A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM161A-to-partner and partner-to-FAM161A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM161A versus TRAF3 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161A→partner) and Y-score (partner→FAM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRAF3 →	+1.043	+0.706	<.001	<.001	3	2
LSCC	RNASEH1-AS1 →	+0.734	+0.601	<.001	<.001	3	2
BRCA	TGFBR3L →	+0.697	+0.557	.004	.002	3	2
BRCA	ACOT7 →	+0.947	+0.502	.002	.008	3	2
UCEC	LRRC23 →	+1.271	+0.421	.002	.004	3	2
UCEC	DYDC2 →	+1.374	+0.561	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,106 associations by consensus.

FAM161A vs TRAF3 — BRCA

Explore this scatter interactively →