FAM161A

Across TCGA cell cohorts, FAM161A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,775 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM161A-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, DNA biosynthetic process, and Positive regulation of DNA biosynthetic process. Each is linked with FAM161A in more than 17 cancer types. Because this analysis shows association rather than direction, both FAM161A-to-partner and partner-to-FAM161A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by FAM161A-low versus FAM161A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161A→partner) and Y-score (partner→FAM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of DNA metabolic process →	+0.063	+0.724	<.001	<.001	3	18
STOMACH	DNA biosynthetic process →	+0.073	+0.971	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA biosynthetic process →	+0.112	+1.189	<.001	<.001	3	17
BONE	Heterochromatin formation →	+0.104	+1.152	<.001	.001	3	17
LUNG_SCLC	Regulation of centrosome duplication →	+0.123	+0.879	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Protein localization to cilium →	+0.091	+1.538	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,775 associations by consensus.

Positive regulation of DNA metabolic process by FAM161A expression — LUNG_SCLC

Explore this box plot interactively →