FAM161A

Across TCGA cell cohorts, FAM161A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM161A-associated genes across cancer lineages are PRAMEF18, ITGAD, and FAM205A. Each is linked with FAM161A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM161A-to-partner and partner-to-FAM161A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF18 grouped by FAM161A-low versus FAM161A-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161A→partner) and Y-score (partner→FAM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PRAMEF18 →	+0.026	+4.930	<.001	.008	3	1
LARGE_INTESTINE	ITGAD →	+0.009	+2.925	.003	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.025	+3.614	<.001	.006	3	1
BLOOD_Leukemia	MYL2 →	+0.572	+4.152	<.001	.009	3	1
BLOOD_Leukemia	IFNG →	+0.228	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PRAMEF18 by FAM161A expression — SOFT_TISSUE

Explore this box plot interactively →