FAM160B2

Across TCGA patient cohorts, FAM160B2 mutation is significantly associated with the RNA expression of many other genes, with 1,468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160B2-associated genes across cancer lineages are MIR8075, SLC7A11, and NOCT. Each is linked with FAM160B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160B2-to-partner and partner-to-FAM160B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8075 grouped by FAM160B2-low versus FAM160B2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160B2→partner) and Y-score (partner→FAM160B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR8075 →	+0.259	+4.857	<.001	.004	3	2
UCEC	SLC7A11 →	+0.729	+1.925	.003	.005	3	2
UCEC	NOCT →	+0.753	+2.008	<.001	.005	3	2
UCEC	AP1S3 →	+0.639	+4.000	<.001	<.001	3	2
UCEC	DCLRE1C →	+0.378	+2.627	.002	.005	3	2
UCEC	SKA1 →	+0.709	+3.024	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,468 associations by consensus.

MIR8075 by FAM160B2 expression — BRCA

Explore this box plot interactively →