FAM160B2

Across TCGA patient cohorts, FAM160B2 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160B2-associated genes across cancer lineages are Cyclin-B1, EGFR_pY1068, and FoxM1. Each is linked with FAM160B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM160B2-to-partner and partner-to-FAM160B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by FAM160B2-low versus FAM160B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160B2→partner) and Y-score (partner→FAM160B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.870	+3.169	<.001	<.001	3	3
UCEC	EGFR_pY1068 →	-0.265	-2.000	.007	.030	3	3
UCEC	FoxM1 →	+0.235	+1.884	.020	.030	3	3
COAD	GAPDH →	+0.586	+2.815	.035	.036	3	2
UCEC	eEF2 →	+0.290	+2.321	.039	.033	3	2
UCEC	JNK_pT183_Y185 →	-0.164	-1.986	.013	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Cyclin-B1 by FAM160B2 expression — UCEC

Explore this box plot interactively →