FAM160B2

Across TCGA cell cohorts, FAM160B2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM160B2-associated genes across cancer lineages are C10orf53, METTL21C, and KRTAP10-1. Each is linked with FAM160B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160B2-to-partner and partner-to-FAM160B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by FAM160B2-low versus FAM160B2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160B2→partner) and Y-score (partner→FAM160B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C10orf53 →	+0.013	+3.217	<.001	.006	3	2
BLOOD_Lymphoma	METTL21C →	+0.019	+4.714	.004	.002	3	1
CNS	KRTAP10-1 →	+0.045	+4.981	<.001	.008	3	1
BLOOD_Leukemia	APOC3 →	+0.209	+3.475	<.001	.006	3	1
BLOOD_Leukemia	CST8 →	+0.034	+3.969	<.001	.009	3	1
BLOOD_Leukemia	WDR72 →	+0.612	+3.551	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

C10orf53 by FAM160B2 expression — LARGE_INTESTINE

Explore this box plot interactively →