FAM160B1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FAM160B1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAM160B1 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FAM160B1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM160B1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where FAM160B1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSTertileII,III,IV0.9131.000.03930view →
CCRCCOSMedianIV0.1230.785.00925view →
PDACDFSQuartileII,III,IV0.9950.630.00210view →
GBMOSMedianAll0.8970.639.0037view →
LUADOSMedianAll0.9650.793.0401view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAM160B1–COAD (DFS)

Kaplan–Meier survival curve for FAM160B1 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration