FAM160B1

Across TCGA pan-cancer cohorts, FAM160B1 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of FAM160B1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where FAM160B1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types FAM160B1 is over-expressed in tumor, although a few such as LSCC and LUAD show the opposite, repressed pattern.

LSCC, LUAD, and HNSC are the cancer types where FAM160B1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM160B1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Male	III,IV	−0.235	<.001	8	view →
LUAD	Female	II,III,IV	−0.173	<.001	8	view →
HNSC	Male	II,III,IV	+0.132	<.001	8	view →
COAD	Female	III,IV	+0.120	.045	1	view →
CCRCC	Male	All	−0.065	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

FAM160B1–LSCC

Open the LSCC breakdown →