FAM160B1

Across TCGA patient cohorts, FAM160B1 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160B1-associated genes across cancer lineages are 14-3-3_beta, MEK1, and PCNA. Each is linked with FAM160B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160B1-to-partner and partner-to-FAM160B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by FAM160B1-low versus FAM160B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160B1→partner) and Y-score (partner→FAM160B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.098	-2.432	.009	.018	3	2
UCEC	MEK1 →	+0.418	+2.169	.002	.003	3	2
UCEC	PCNA →	+0.179	+2.459	.027	.019	3	2
UCEC	Rad50 →	-0.263	-2.169	.003	.003	3	2
UCEC	ATM →	-0.503	-1.986	.003	.029	3	2
UCEC	Caspase-7-cleavedD198 →	+0.479	+1.604	.031	.041	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

14-3-3_beta by FAM160B1 expression — UCEC

Explore this box plot interactively →