FAM160B1

Across TCGA cell cohorts, FAM160B1 mutation is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM160B1-associated genes across cancer lineages are MAGEB5, PIRT, and SRRD. Each is linked with FAM160B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160B1-to-partner and partner-to-FAM160B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by FAM160B1-low versus FAM160B1-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160B1→partner) and Y-score (partner→FAM160B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	PIRT →	+0.006	+4.643	<.001	.008	3	1
LARGE_INTESTINE	SRRD →	+0.849	+3.169	<.001	.009	3	1
LARGE_INTESTINE	GCAT →	+1.368	+3.169	<.001	.006	3	1
LARGE_INTESTINE	SNU13 →	+0.495	+3.364	.002	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.587	+3.451	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

MAGEB5 by FAM160B1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →